| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T67849 | ||||
| Target Name | PI3-kinase delta (PIK3CD) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate | Drug Info | IC50 = 6000 nM | [1] | |
| LY-292223 | Drug Info | IC50 = 14000 nM | [1] | ||
| References | |||||
| REF 1 | LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family. Bioorg Med Chem Lett. 2001 Apr 9;11(7):909-13. | ||||
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