Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T72515 | ||||
Target Name | Interleukin 1 receptor type 1 (IL1R1) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | Anakinra | Drug Info | IC50 = 1.935 nM | [1] | |
References | |||||
REF 1 | IL-1 receptor accessory protein-Ig/IL-1 receptor type II-Ig heterodimer inhibits IL-1 response more strongly than other IL-1 blocking biopharmaceutical agents. J Clin Immunol. 2011 Jun;31(3):455-64. | ||||
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