| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T87463 | ||||
| Target Name | Fungal Protein kinase A (Fung ypkA) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | BALANOL | Drug Info | Ki = 4.7 nM | [1] | |
| Ro-4396686 | Drug Info | IC50 = 9010 nM | [2] | ||
| References | |||||
| REF 1 | Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. J Med Chem. 2005 Sep 8;48(18):5613-38. Address; | ||||
| REF 2 | Biological evaluation of a multi-targeted small molecule inhibitor of tumor-induced angiogenesis. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1950-3. | ||||
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