| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T89323 | ||||
| Target Name | Mixed lineage kinase 2 (MAP3K10) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | CEP-5104 | Drug Info | IC50 = 1582 nM | [1] | |
| CEP-6331 | Drug Info | IC50 = 1855 nM | [1] | ||
| References | |||||
| REF 1 | Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-linea... J Med Chem. 2008 Sep 25;51(18):5680-9. | ||||
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