| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T94788 | ||||
| Target Name | Branched-chain-amino-acid transaminase 2 (BCAT2) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | N'-(phenylsulfonyl)benzofuran-2-carbohydrazide | Drug Info | IC50 = 18300 nM | [1] | |
| N'-(phenylsulfonyl)quinoline-6-carbohydrazide | Drug Info | IC50 = 13300 nM | [1] | ||
| References | |||||
| REF 1 | The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. | ||||
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