Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T96627 | ||||
Target Name | C-X-C motif chemokine 2 (CXCL2) | ||||
Type of Target |
Clinical trial |
||||
Action against Disease Model | Laquinamod | Drug Info | Experimental evidence to date, derived mostly from animal models of multiple sclerosis, suggests that laquinimod may mediate its effects via modulating pro-inflammatory immune responses and interfering with cell trafficking, as well as potentially acting directly in the central nervous system to limit demyelination and axonal injury. | [1] | |
References | |||||
REF 1 | Laquinimod in multiple sclerosis. Clin Immunol. 2012 Jan;142(1):38-43. | ||||
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