| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T98315 | ||||
| Target Name | SOAT2 messenger RNA (SOAT2 mRNA) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | Oleic acid anilide | Drug Info | IC50 = 170 nM | [2] | |
| PYRIPYROPENE A | Drug Info | IC50 = 640 nM | [1] | ||
| References | |||||
| REF 1 | Saucerneol B derivatives as human acyl-CoA: cholesterol acyltransferase inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15(2):385-8. | ||||
| REF 2 | Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5580-3. | ||||
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