| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T98896 | ||||
| Target Name | Aggrecanase (ADAMTS5) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | SC-44463 | Drug Info | IC50 = 368 nM | [1] | |
| References | |||||
| REF 1 | Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivati... J Med Chem. 2001 Oct 11;44(21):3347-50. | ||||
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