Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T27770
(Former ID: TTDI01297)
|
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| Target Name |
Late inward sodium current (LISC)
|
|||||
| Gene Name |
NO-GeName
|
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| Target Type |
Clinical trial target
|
[1] | ||||
| Disease | [+] 2 Target-related Diseases | + | ||||
| 1 | Genetic cardiac arrhythmia [ICD-11: BC65] | |||||
| 2 | Ischemic heart disease [ICD-11: BA40-BA6Z] | |||||
| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Clinical Trial Drug(s) | [+] 1 Clinical Trial Drugs | + | ||||
| 1 | GS-6615 | Drug Info | Phase 3 | Ischemic heart disease | [2], [3] | |
| Mode of Action | [+] 1 Modes of Action | + | ||||
| Modulator | [+] 1 Modulator drugs | + | ||||
| 1 | GS-6615 | Drug Info | [1] | |||
| Co-Targets | Top | |||||
|---|---|---|---|---|---|---|
| Co-Targets | ||||||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Gilead. | |||||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8413). | |||||
| REF 3 | ClinicalTrials.gov (NCT02300558) Effect of GS-6615 on Shortening of the QT Interval, Safety, and Tolerability in Adults With Long QT-3 Syndrome. U.S. National Institutes of Health. | |||||
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