Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T71484
(Former ID: TTDS00300)
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| Target Name |
Fungal Microtubule (Fung MicroTU)
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| Synonyms |
Keratin
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| Gene Name |
NO-GeName
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| Target Type |
Successful target
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[1] | ||||
| Disease | [+] 1 Target-related Diseases | + | ||||
| 1 | Dermatophytosis [ICD-11: 1F28] | |||||
| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Approved Drug(s) | [+] 1 Approved Drugs | + | ||||
| 1 | Griseofulvin | Drug Info | Approved | Ringworm infection | [2], [3] | |
| Mode of Action | [+] 1 Modes of Action | + | ||||
| Inducer | [+] 1 Inducer drugs | + | ||||
| 1 | Griseofulvin | Drug Info | [1], [4] | |||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Dermatophyte infections. Am Fam Physician. 2003 Jan 1;67(1):101-8. | |||||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||||
| REF 3 | Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality. Ther Clin Risk Manag. 2005 Dec;1(4):299-306. | |||||
| REF 4 | Formation of Mallory body-like inclusions and cell death induced by deregulated expression of keratin 18. Mol Biol Cell. 2002 Oct;13(10):3441-51. | |||||
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