Target Information
| Target General Information | Top | |||||
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| Target ID |
T88213
(Former ID: TTDI02558)
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| Target Name |
Vasoactive intestinal polypeptide (VIP)
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| Synonyms |
Vasoactive intestinal peptide; VIP peptides; Peptide histidine valine 42; Intestinal peptide PHV-42
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| Gene Name |
VIP
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| Target Type |
Literature-reported target
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[1] | ||||
| Function |
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
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| UniProt ID | ||||||
| Sequence |
MDTRNKAQLLVLLTLLSVLFSQTSAWPLYRAPSALRLGDRIPFEGANEPDQVSLKEDIDM
LQNALAENDTPYYDVSRNARHADGVFTSDFSKLLGQLSAKKYLESLMGKRVSSNISEDPV PVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGESPDFPEELEK Click to Show/Hide
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| 3D Structure | Click to Show 3D Structure of This Target | AlphaFold | ||||
| HIT2.0 ID | T17A6S | |||||
| Target Regulators | Top | |||||
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| Target-regulating Transcription Factors | ||||||
| References | Top | |||||
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| REF 1 | The effect of vasoactive intestinal polypeptide on gastric acid secretion is predominantly mediated by somatostatin. Gastroenterology. 1991 May;100(5 Pt 1):1195-200. | |||||
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