Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T96396
(Former ID: TTDI02601)
|
|||||
| Target Name |
Prohibitin (PHB)
|
|||||
| Synonyms |
PHB1; HEL-S-54e; HEL-215
|
|||||
| Gene Name |
PHB
|
|||||
| Target Type |
Literature-reported target
|
[1] | ||||
| Function |
It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. Prohibitin inhibits DNA synthesis.
Click to Show/Hide
|
|||||
| UniProt ID | ||||||
| Sequence |
MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ Click to Show/Hide
|
|||||
| 3D Structure | Click to Show 3D Structure of This Target | AlphaFold | ||||
| Target Regulators | Top | |||||
|---|---|---|---|---|---|---|
| Target-regulating microRNAs | ||||||
| Target-interacting Proteins | ||||||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Prohibitin: a potential target for new therapeutics. Trends Mol Med. 2005 Apr;11(4):192-7. | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.