Target Information
| Target General Information | Top | |||||
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| Target ID |
T96704
(Former ID: TTDR00986)
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| Target Name |
Heat shock protein 40 (HSP40)
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| Synonyms |
Heat shock 40 kDa protein 1; HSP40; HDJ-1; DnaJ protein homolog 1; DnaJ homolog subfamily B member 1; DNAJB1
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| Gene Name |
DNAJB1
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| Target Type |
Literature-reported target
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[1] | ||||
| Function |
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.
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| BioChemical Class |
Heat shock protein
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| UniProt ID | ||||||
| Sequence |
MGKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRK
REIFDRYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRN GEEGMDIDDPFSGFPMGMGGFTNVNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCT KKMKISHKRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNNIPADIVFVLK DKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGE GLPLPKTPEKRGDLIIEFEVIFPERIPQTSRTVLEQVLPI Click to Show/Hide
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| 3D Structure | Click to Show 3D Structure of This Target | AlphaFold | ||||
| ADReCS ID | BADD_A05386 | |||||
| Target Regulators | Top | |||||
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| Target-interacting Proteins | ||||||
| References | Top | |||||
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| REF 1 | Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular a... Hum Mol Genet. 2002 Mar 1;11(5):515-23. | |||||
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