Target Information
Target General Information | Top | |||||
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Target ID |
T99664
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Target Name |
HUMAN l-lactate dehydrogenase (LDH)
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Synonyms |
Renal carcinoma antigen NY-REN; LDH
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Gene Name |
LDHA; LDHB; LDHC
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Function |
Catalyzes the conversion of lactate to pyruvate and back, as it converts NAD+ to NADH and back. Expressed extensively in body tissues, such as blood cells and heart muscle. Functions asa marker of common injuries and disease such as heart failure because it is released during tissue damage
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BioChemical Class |
Short-chain dehydrogenases reductase
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UniProt ID | ||||||
Sequence |
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKG
EMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFI IPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGV HPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYE VIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGI SDLVKVTLTSEEEARLKKSADTLWGIQKELQF Click to Show/Hide
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Target Poor or Non Binders | Top | |||||
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Target Poor or Non Binders |
References | Top | |||||
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REF 1 | Hematological Findings and Complications of COVID-19. Am J Hematol. 2020 Apr 13. doi: 10.1002/ajh.25829. |
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