Resistance mutation info of target
| Target General Information | |||||||||||||||||||||||
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| Target ID | T49995 | ||||||||||||||||||||||
| Target Name | Bacterial Arylamine N-acetyltransferase (nhoA) | ||||||||||||||||||||||
| Gene Name | nhoA | ||||||||||||||||||||||
| Species | Mycobacterium tuberculosis | ||||||||||||||||||||||
| UniProt ID | NAT_MYCTU | ||||||||||||||||||||||
| Sequence |
MALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADK LVLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGS GGCYLVDVGFGGQTPTSPLRLETGAVQPTTHEPYRLEDRVDGFVLQAMVRDTWQTLYEFT TQTRPQIDLKVASWYASTHPASKFVTGLTAAVITDDARWNLSGRDLAVHRAGGTEKIRLA DAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGADAP [Mycobacterium t uberculosis] |
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| Drug and Corresponding Resistance Mutations | |||||||||||||||||||||||
| Mutation Info | Missense: G207E | ||||||||||||||||||||||
| Drugs |
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| Mutation Info | Missense: G67R | ||||||||||||||||||||||
| Drugs |
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| References | |||||||||||||||||||||||
| REF 1 | Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2003 Apr;47(4):1241-50. | ||||||||||||||||||||||
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