Resistance mutation info of target
| Target General Information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Target ID | T52227 | |||||||||||||||||
| Target Name | Bacterial Thymidylate synthase (thyA) | |||||||||||||||||
| Gene Name | thyA | |||||||||||||||||
| Species | Mycobacterium tuberculosis | |||||||||||||||||
| UniProt ID | TYSY_MYCTU | |||||||||||||||||
| Sequence |
MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV [Mycobacterium tuberculosis] |
|||||||||||||||||
| Drug and Corresponding Resistance Mutations | ||||||||||||||||||
| Mutation Info | Missense: R222G | |||||||||||||||||
| Drugs |
|
|||||||||||||||||
| Mutation Info | Missense: T202A | |||||||||||||||||
| Drugs |
|
|||||||||||||||||
| References | ||||||||||||||||||
| REF 1 | The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria. Mol Microbiol. 2004 Jul;53(1):275-82. | |||||||||||||||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.