Resistance mutation info of target
| Target General Information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Target ID | T83793 | |||||||||||||||||
| Target Name | HIV Negative factor (nef) | |||||||||||||||||
| Gene Name | nef | |||||||||||||||||
| Species | Human immunodeficiency virus type 1 (HIV-1) | |||||||||||||||||
| UniProt ID | NEF_HV1A2 | |||||||||||||||||
| Sequence |
MGGKWSKRSMGGWSAIRERMRRAEPRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCA WLEAQEEEEVGFPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYH TQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDA EKEVLVWRFDSKLAFHHMARELHPEYYKDC [Human immunodeficiency virus type 1 (HIV-1)] |
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| Drug and Corresponding Resistance Mutations | ||||||||||||||||||
| Mutation Info | Missense: D174N | |||||||||||||||||
| Drugs |
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| References | ||||||||||||||||||
| REF 1 | Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.Antimicrob Agents Chemother.2010 Apr;54(4):1512-9. | |||||||||||||||||
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