Drug Information

Drug General Information
Drug ID
D09EGZ
Former ID
DAP000165
Drug Name
Chloroquine
Synonyms
Amokin; Aralen; Arechin; Arechine; Arequin; Arolen; Arthrochin; Artrichin; Avlochlor; Avloclor; Bemaco; Bemaphate; Bemasulph; Benaquin; Bipiquin; Capquin; Chemochin; Chingamin; Chloraquine; Chlorochin; Chlorochine; Chlorochinum; Chloroin; Chloroquin; Chloroquina; Chloroquinium; Chloroquinum; Chlorquin; Cidanchin; Clorochina; Cloroquina; Cocartrit; Delagil; Dichinalex; Elestol; Gontochin; Heliopar; Imagon; Iroquine; Khingamin; Klorokin; Lapaquin; Malaquin; Malaren; Malarex; Mesylith; Miniquine; Neochin; Nivachine; Pfizerquine; Quinachlor; Quinagamin; Quinagamine; Quinercyl; Quingamine; Quinilon; Quinoscan; Resochen; Resochin; Resoquina; Resoquine; Reumachlor; Reumaquin; Rivoquine; Ronaquine; Roquine; Sanoquin; Silbesan;Siragan; Solprina; Sopaquin; Tanakan; Tanakene; Tresochin; Trochin; Aralen HCl; Chloroquine phosphate; Clorochina [DCIT]; Gontochin phosphate; Nivaquine B; Ipsen 225; RP 3377; SN 6718; ST 21; W 7618;WIN 244; Chloroquine (VAN); Chloroquine Bis-Phosphoric Acid; Chloroquine FNA (TN); Chloroquinum [INN-Latin]; Cloroquina [INN-Spanish]; Dawaquin (TN); RP-3377; Resochin (TN); SN-7618; ST 21 (pharmaceutical); CU-01000012392-2; Chloroquine (USP/INN); Chloroquine [USAN:INN:BAN]; Ro 01-6014/N2; Malaquin (*Diphosphate*); {4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine; N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine; N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine; (+)-Chloroquine; (-)-Chloroquine; (R)-(-)-Chloroquine; 3377 RP opalate; 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline; 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
Drug Type
Small molecular drug
Indication Malaria [ICD10:B54] Approved [536135], [540925]
Therapeutic Class
Antimalarials
Company
Medreich Sterilab Ltd
Structure
Download
2D MOL

3D MOL
Formula
C18H26ClN3
InChI
InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)
InChIKey
WHTVZRBIWZFKQO-UHFFFAOYSA-N
CAS Number
CAS 54-05-7
PubChem Compound ID
2719
PubChem Substance ID
9827, 447935, 596572, 5050990, 7849425, 7978921, 8151759, 10526125, 11335579, 11360818, 11363006, 11365568, 11368130, 11371321, 11373917, 11376292, 11404351, 11405289, 11461790, 11466576, 11467696, 11483910, 11486252, 11487943, 11490157, 11492094, 11493946, 11528736, 14776983, 26675665, 29221876, 46506925, 47217037, 47291356, 47440521, 47440522, 47885638, 48035387, 48110720, 48185227, 48259487, 49635547, 49681217, 49698849, 49846799, 50111008, 53787949, 53788124, 56310729, 57321414
ChEBI ID
ChEBI:3638
SuperDrug ATC ID
P01BA01
SuperDrug CAS ID
cas=000054057
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) Duffy antigen chemokine receptor Target Info Modulator [556264]
References
Ref 536135Opportunities and challenges in antiparasitic drug discovery. Nat Rev Drug Discov. 2005 Sep;4(9):727-40.
Ref 540925(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5535).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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