Drug Information

Drug General Information
Drug ID
DX0AZZ
Drug Name
[1-(3H-Imidazol-4-ylmethyl)-7-pyridin-4-yl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-(2-trifluoromethoxy-phenyl)-methanone
Synonyms
CHEMBL430778
Indication Discovery agent Investigative [1587926]
Formula
C26H22F3N5O2
Canonical SMILES
FC(F)(F)Oc1ccccc1C(=O)N2CCN(Cc3c[nH]cn3)c4ccc(cc4C2)c5ccncc5
InChI
InChI=1S/C26H22F3N5O2/c27-26(28,29)36-24-4-2-1-3-22(24)25(35)34-12-11-33(16-21-14-31-17-32-21)23-6-5-19(13-20(23)15-34)18-7-9-30-10-8-18/h1-10,13-14,17H,11-12,15-16H2,(H,31,32)
InChIKey
YBROKHNFEQXGSA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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