Drug Information
Drug General Information | |||||
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Drug ID |
DX0HKJ
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Drug Name |
SID124349812
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Synonyms |
CHEMBL243917
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C28H19F4N5O3
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Canonical SMILES |
Fc1ccc(cc1NC(=O)Nc2ccc(Oc3ccc4[nH]c(NC(=O)c5ccccc5)nc4c3)cc2)C(F)(F)F
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InChI |
InChI=1S/C28H19F4N5O3/c29-21-12-6-17(28(30,31)32)14-23(21)36-27(39)33-18-7-9-19(10-8-18)40-20-11-13-22-24(15-20)35-26(34-22)37-25(38)16-4-2-1-3-5-16/h1-15H,(H2,33,36,39)(H2,34,35,37,38)
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InChIKey |
BUBCSTHPMRUDOR-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
Angiopoietin 1 receptor | Target Info | [1587926] | |||
NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
PANTHER Pathway | Angiogenesis | ||||
VEGF signaling pathwayP00005:Angiogenesis | |||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
Beta3 integrin cell surface interactions | |||||
Signaling events mediated by TCPTP | |||||
SHP2 signaling | |||||
S1P1 pathway | |||||
VEGF and VEGFR signaling network | |||||
Integrins in angiogenesis | |||||
Signaling events mediated by VEGFR1 and VEGFR2 | |||||
Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
References |
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