Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX0UZ3
|
||||
| Drug Name |
N-methyl-5-(2-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)phenyl)ethynyl)picolinamide
|
||||
| Synonyms |
CHEMBL450024
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H18F3N3O2
|
||||
| Canonical SMILES |
CNC(=O)c1ccc(cn1)C#Cc2cc(ccc2C)C(=O)Nc3cccc(c3)C(F)(F)F
|
||||
| InChI |
InChI=1S/C24H18F3N3O2/c1-15-6-9-18(22(31)30-20-5-3-4-19(13-20)24(25,26)27)12-17(15)10-7-16-8-11-21(29-14-16)23(32)28-2/h3-6,8-9,11-14H,1-2H3,(H,28,32)(H,30,31)
|
||||
| InChIKey |
ZMHVJFIIASNLTM-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.