Drug Information

Drug General Information
Drug ID
DX1FKD
Drug Name
1-[(R)-1-(4-Benzoyl-piperidine-1-carbonyl)-4-oxo-4-pyrrolidin-1-yl-butyl]-3-m-tolyl-urea
Synonyms
CHEMBL420658
Indication Discovery agent Investigative [1587926]
Formula
C29H36N4O4
Canonical SMILES
Cc1cccc(NC(=O)N[C@H](CCC(=O)N2CCCC2)C(=O)N3CCC(CC3)C(=O)c4ccccc4)c1
InChI
InChI=1S/C29H36N4O4/c1-21-8-7-11-24(20-21)30-29(37)31-25(12-13-26(34)32-16-5-6-17-32)28(36)33-18-14-23(15-19-33)27(35)22-9-3-2-4-10-22/h2-4,7-11,20,23,25H,5-6,12-19H2,1H3,(H2,30,31,37)/t25-/m1/s1
InChIKey
HRFMJPIGMOWHLL-RUZDIDTESA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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