Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1GSP
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| Drug Name |
2-cyano-4-(cyclohexylamino)-N-phenethylpyrimidine-5-carboxamide
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| Synonyms |
CHEMBL386506
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H23N5O
|
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| Canonical SMILES |
O=C(NCCc1ccccc1)c2cnc(nc2NC3CCCCC3)C#N
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| InChI |
InChI=1S/C20H23N5O/c21-13-18-23-14-17(19(25-18)24-16-9-5-2-6-10-16)20(26)22-12-11-15-7-3-1-4-8-15/h1,3-4,7-8,14,16H,2,5-6,9-12H2,(H,22,26)(H,23,24,25)
|
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| InChIKey |
UEZMKFGTDYYCKL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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