Drug Information

Drug General Information
Drug ID
DX1KHO
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-cyano-phenyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL154138
Indication Discovery agent Investigative [1587926]
Formula
C28H22BrClN6
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/c4ccc(cc4)C#N)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C28H22BrClN6/c29-22-13-21-4-3-20-14-23(30)5-8-25(20)26(27(21)33-16-22)19-9-11-36(12-10-19)28(34-17-32)35-24-6-1-18(15-31)2-7-24/h1-2,5-8,13-14,16H,3-4,9-12H2,(H,34,35)
InChIKey
FEGKWAUHIFCFFC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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