Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1TSB
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| Drug Name |
(R)-2-amino-4-(3-(cyclopropylethynyl)-4-fluorophenyl)-4-(4-(difluoromethoxy)phenyl)-1-methyl-1H-imidazol-5(4H)-one
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| Synonyms |
CHEMBL1270335
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H18F3N3O2
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| Canonical SMILES |
CN1C(=N[C@](C1=O)(c2ccc(OC(F)F)cc2)c3ccc(F)c(c3)C#CC4CC4)N
|
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| InChI |
InChI=1S/C22H18F3N3O2/c1-28-19(29)22(27-21(28)26,15-6-9-17(10-7-15)30-20(24)25)16-8-11-18(23)14(12-16)5-4-13-2-3-13/h6-13,20H,2-3H2,1H3,(H2,26,27)/t22-/m1/s1
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| InChIKey |
JZQHTDKITQYMAR-JOCHJYFZSA-N
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| Target and Pathway | |||||
| Target(s) | Renin, renal | Target Info | [1587926] | ||
| Cathepsin D | Target Info | [1587926] | |||
| BioCyc Pathway | Thyroid hormone biosynthesis | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | LKB1 signaling events | ||||
| Ceramide signaling pathway | |||||
| Direct p53 effectors | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| References | |||||
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