Drug Information

Drug General Information
Drug ID
DX2UTR
Drug Name
1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-phenylmethanesulfonyl-piperidin-4-yl)-ethanone
Synonyms
CHEMBL328743
Indication Discovery agent Investigative [1587926]
Formula
C33H36Br2ClN3O3S
Canonical SMILES
Clc1cc(Br)c2[C@@H](C3CCN(CC3)C(=O)CC4CCN(CC4)S(=O)(=O)Cc5ccccc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C33H36Br2ClN3O3S/c34-27-17-26-7-6-25-18-28(36)19-29(35)31(25)32(33(26)37-20-27)24-10-12-38(13-11-24)30(40)16-22-8-14-39(15-9-22)43(41,42)21-23-4-2-1-3-5-23/h1-5,17-20,22,24,32H,6-16,21H2/t32-/m1/s1
InChIKey
FFNXZDBGNUKYOO-JGCGQSQUSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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