Drug Information
| Drug General Information | |||||
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| Drug ID |
DX2UVE
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| Drug Name |
1-(4-methoxyphenyl)-3-[19-methyl-3-(2-methylpropyl)-14-oxo-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl]urea
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| Synonyms |
CHEMBL218816
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C32H32N6O3
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| Canonical SMILES |
COc1ccc(NC(=O)Nc2ccc3c(c2)c4c5CNC(=O)c5c6c(CCc7nn(C)cc67)c4n3CC(C)C)cc1
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| InChI |
InChI=1S/C32H32N6O3/c1-17(2)15-38-26-12-7-19(35-32(40)34-18-5-8-20(41-4)9-6-18)13-22(26)28-23-14-33-31(39)29(23)27-21(30(28)38)10-11-25-24(27)16-37(3)36-25/h5-9,12-13,16-17H,10-11,14-15H2,1-4H3,(H,33,39)(H2,34,35,40)
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| InChIKey |
AQTHIBWLFXHXGG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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