Drug Information

Drug General Information
Drug ID
DX3IAB
Drug Name
6-[(3'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile
Synonyms
CHEMBL128371
Indication Discovery agent Investigative [1587926]
Formula
C33H23ClF3N5O3
Canonical SMILES
CN1C(=C(C=C(C#N)C1=O)c2ccc(OC(F)(F)F)cc2)COC(c3ccc(C#N)c(c3)c4cccc(Cl)c4)c5cncn5C
InChI
InChI=1S/C33H23ClF3N5O3/c1-41-19-40-17-29(41)31(22-6-7-23(15-38)27(13-22)21-4-3-5-25(34)12-21)44-18-30-28(14-24(16-39)32(43)42(30)2)20-8-10-26(11-9-20)45-33(35,36)37/h3-14,17,19,31H,18H2,1-2H3
InChIKey
IGCORMDACWRGMB-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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