Drug Information

Drug General Information
Drug ID
DX3PLB
Drug Name
6-[(3'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-5-(3,5-dichloro-phenyl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
Synonyms
CHEMBL129578
Indication Discovery agent Investigative [1587926]
Formula
C32H22Cl3N5O2
Canonical SMILES
CN1C(=C(C=C(C#N)C1=O)c2cc(Cl)cc(Cl)c2)COC(c3ccc(C#N)c(c3)c4cccc(Cl)c4)c5cncn5C
InChI
InChI=1S/C32H22Cl3N5O2/c1-39-18-38-16-29(39)31(20-6-7-21(14-36)27(11-20)19-4-3-5-24(33)8-19)42-17-30-28(12-23(15-37)32(41)40(30)2)22-9-25(34)13-26(35)10-22/h3-13,16,18,31H,17H2,1-2H3
InChIKey
JQBMSMWRNHYILW-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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