Drug Information

Drug General Information
Drug ID
DX3QKX
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-dimethylamino-benzyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL440365
Indication Discovery agent Investigative [1587926]
Formula
C30H30BrClN6
Canonical SMILES
CN(C)c1ccc(C\\N=C(\\NC#N)/N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)cc1
InChI
InChI=1S/C30H30BrClN6/c1-37(2)26-8-3-20(4-9-26)17-35-30(36-19-33)38-13-11-21(12-14-38)28-27-10-7-25(32)16-22(27)5-6-23-15-24(31)18-34-29(23)28/h3-4,7-10,15-16,18H,5-6,11-14,17H2,1-2H3,(H,35,36)
InChIKey
KZVFXLKTHYAUEE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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