Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3RBZ
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| Drug Name |
2-methyl-3-(5-methyl-3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
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| Synonyms |
CHEMBL218431
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C31H31F3N6O2
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| Canonical SMILES |
CNc1nccc(n1)c2cc(C)cnc2Oc3cccc(C(=O)Nc4cc(ccc4N5CCCCC5)C(F)(F)F)c3C
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| InChI |
InChI=1S/C31H31F3N6O2/c1-19-16-23(24-12-13-36-30(35-3)39-24)29(37-18-19)42-27-9-7-8-22(20(27)2)28(41)38-25-17-21(31(32,33)34)10-11-26(25)40-14-5-4-6-15-40/h7-13,16-18H,4-6,14-15H2,1-3H3,(H,38,41)(H,35,36,39)
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| InChIKey |
WDEPCTJBPQDCEB-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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