Drug Information

Drug General Information
Drug ID
DX3RTD
Drug Name
1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-3-yl)-ethanone
Synonyms
CHEMBL155363
Indication Discovery agent Investigative [1587926]
Formula
C26H24Br2ClN3O2
Canonical SMILES
[O-][n+]1cccc(CC(=O)N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)c1
InChI
InChI=1S/C26H24Br2ClN3O2/c27-20-11-19-4-3-18-12-21(29)13-22(28)24(18)25(26(19)30-14-20)17-5-8-31(9-6-17)23(33)10-16-2-1-7-32(34)15-16/h1-2,7,11-15,17,25H,3-6,8-10H2/t25-/m1/s1
InChIKey
CJIVZNOHIDIINJ-RUZDIDTESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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