Drug Information

Drug General Information
Drug ID
DX3ULU
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-cyclopentanecarbonyl-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL202825
Indication Discovery agent Investigative [1587926]
Formula
C31H33BrClN5O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCc4cccnc4)C(=O)C5CCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C31H33BrClN5O2/c32-24-14-23-8-7-22-15-25(33)9-10-26(22)29(28(23)35-18-24)37-12-13-38(31(40)21-5-1-2-6-21)27(19-37)30(39)36-17-20-4-3-11-34-16-20/h3-4,9-11,14-16,18,21,27,29H,1-2,5-8,12-13,17,19H2,(H,36,39)
InChIKey
NIOSFAVPXNLLPG-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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