Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3ZEF
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| Drug Name |
5-Chloro-benzofuran-2-carboxylic acid {(S)-2-cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-amide
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| Synonyms |
CHEMBL198420
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H32ClN3O4
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3oc4ccc(Cl)cc4c3)cc1
|
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| InChI |
InChI=1S/C27H32ClN3O4/c1-34-22-10-8-21(9-11-22)29-13-14-30-26(32)23(15-18-5-3-2-4-6-18)31-27(33)25-17-19-16-20(28)7-12-24(19)35-25/h7-12,16-18,23,29H,2-6,13-15H2,1H3,(H,30,32)(H,31,33)/t23-/m0/s1
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| InChIKey |
JWJMPDHKYJTJFE-QHCPKHFHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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