Drug Information
| Drug General Information | |||||
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| Drug ID |
DX4AAU
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| Drug Name |
2-(3-{3-[(3,4-Bis-trifluoromethyl-benzoyl)-(2-cyclopropyl-3-[1,2,4]oxadiazol-3-yl-phenyl)-amino]-propyl}-phenoxy)-2-methyl-propionic acid
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| Synonyms |
CHEMBL101123
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C33H29F6N3O5
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| Canonical SMILES |
CC(C)(Oc1cccc(CCCN(C(=O)c2ccc(c(c2)C(F)(F)F)C(F)(F)F)c3cccc(c4nocn4)c3C5CC5)c1)C(=O)O
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| InChI |
InChI=1S/C33H29F6N3O5/c1-31(2,30(44)45)47-22-8-3-6-19(16-22)7-5-15-42(26-10-4-9-23(27(26)20-11-12-20)28-40-18-46-41-28)29(43)21-13-14-24(32(34,35)36)25(17-21)33(37,38)39/h3-4,6,8-10,13-14,16-18,20H,5,7,11-12,15H2,1-2H3,(H,44,45)
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| InChIKey |
XMGJEASDMJAFLB-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Peroxisome proliferator activated receptor gamma | Target Info | [1587926] | ||
| Peroxisomeproliferator activated receptor delta | Target Info | [1587926] | |||
| PANTHER Pathway | CCKR signaling map STP00057:Wnt signaling pathway | ||||
| Pathway Interaction Database | Noncanonical Wnt signaling pathway | ||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Signaling events mediated by HDAC Class I | |||||
| RXR and RAR heterodimerization with other nuclear receptor | |||||
| Regulation of retinoblastoma proteinps1pathway:Presenilin action in Notch and Wnt signaling | |||||
| WikiPathways | Wnt Signaling Pathway Netpath | ||||
| Nuclear Receptors in Lipid Metabolism and Toxicity | |||||
| Differentiation of white and brown adipocyte | |||||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
| Transcriptional Regulation of White Adipocyte Differentiation | |||||
| Adipogenesis | |||||
| SREBP signalling | |||||
| Nuclear ReceptorsWP399:Wnt Signaling Pathway and Pluripotency | |||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Vitamin D Receptor Pathway | |||||
| Ectoderm Differentiation | |||||
| Nuclear Receptors | |||||
| References | |||||
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