Drug Information

Drug General Information
Drug ID
DX4DWO
Drug Name
1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(4-dimethylamino-phenyl)-ethanone
Synonyms
CHEMBL172397
Indication Discovery agent Investigative [1587926]
Formula
C28H31ClN4O
Canonical SMILES
CN(C)c1ccc(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)cc1
InChI
InChI=1S/C28H31ClN4O/c1-31(2)24-10-5-20(6-11-24)18-26(34)32-14-16-33(17-15-32)28-25-12-9-23(29)19-22(25)8-7-21-4-3-13-30-27(21)28/h3-6,9-13,19,28H,7-8,14-18H2,1-2H3
InChIKey
BXMOASUHWDVRIC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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