Drug Information

Drug General Information
Drug ID
DX4DWP
Drug Name
4-{2-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid amide
Synonyms
CHEMBL364342
Indication Discovery agent Investigative [1587926]
Formula
C27H29Br2ClN4O2
Canonical SMILES
NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@@H]3c4ncc(Br)cc4C=Cc5cc(Cl)cc(Br)c35)CC1
InChI
InChI=1S/C27H29Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h1-2,12-17,25H,3-11H2,(H2,31,36)/t25-/m0/s1
InChIKey
XHJYBXKCAUZIFW-VWLOTQADSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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