Drug Information
| Drug General Information | |||||
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| Drug ID |
DX4JKR
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| Drug Name |
7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-(propan-2-yl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL401876
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H27N5O2
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| Canonical SMILES |
CO\\N=C(/C)\\c1ccc2c(c1)c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c3n2C(C)C
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| InChI |
InChI=1S/C26H27N5O2/c1-13(2)31-21-9-6-15(14(3)29-33-5)10-17(21)23-18-11-27-26(32)24(18)22-16(25(23)31)7-8-20-19(22)12-30(4)28-20/h6,9-10,12-13H,7-8,11H2,1-5H3,(H,27,32)/b29-14+
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| InChIKey |
IIHSBRSDVGUWER-IPPBACCNSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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