Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4RQ5
|
||||
| Drug Name |
1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine
|
||||
| Synonyms |
CHEMBL457984
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H23N7O
|
||||
| Canonical SMILES |
CNc1nccc(n1)c2cccnc2Oc3ccc(Nc4nc5ccccc5n4C)c6ccccc36
|
||||
| InChI |
InChI=1S/C28H23N7O/c1-29-27-31-17-15-22(32-27)20-10-7-16-30-26(20)36-25-14-13-21(18-8-3-4-9-19(18)25)33-28-34-23-11-5-6-12-24(23)35(28)2/h3-17H,1-2H3,(H,33,34)(H,29,31,32)
|
||||
| InChIKey |
FGQULRNTICLCRF-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.