Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4TBS
|
||||
| Drug Name |
19-methyl-7-[(1E)-1-[(2-methylpropoxy)imino]ethyl]-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
|
||||
| Synonyms |
CHEMBL258222
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H35N5O2
|
||||
| Canonical SMILES |
CC(C)CO\\N=C(/C)\\c1ccc2c(c1)c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c3n2CC(C)C
|
||||
| InChI |
InChI=1S/C30H35N5O2/c1-16(2)13-35-25-10-7-19(18(5)33-37-15-17(3)4)11-21(25)27-22-12-31-30(36)28(22)26-20(29(27)35)8-9-24-23(26)14-34(6)32-24/h7,10-11,14,16-17H,8-9,12-13,15H2,1-6H3,(H,31,36)/b33-18+
|
||||
| InChIKey |
XDTHMZDYYMXLKO-DPNNOFEESA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.