Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4TYZ
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| Drug Name |
(S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-methyl-amino)-4-(4-methoxy-phenyl)-2,15-dioxo-11-oxa-3,14-diaza-tricyclo[14.3.1.1*5,9*]henicosa-1(20),5,7,9(21),16,18-hexaen-13-yl]-ethyl}-N-isobutyl-3-methyl-butyramideyramide
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| Synonyms |
CHEMBL1644466
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C38H50N4O8S
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| Canonical SMILES |
COc1ccc(cc1)C2NC(=O)c3cc(cc(c3)C(=O)N[C@@H](COCc4cccc2c4)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)C)N(C)S(=O)(=O)C
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| InChI |
InChI=1S/C38H50N4O8S/c1-23(2)20-39-38(46)32(24(3)4)19-34(43)33-22-50-21-25-9-8-10-27(15-25)35(26-11-13-31(49-6)14-12-26)41-37(45)29-16-28(36(44)40-33)17-30(18-29)42(5)51(7,47)48/h8-18,23-24,32-35,43H,19-22H2,1-7H3,(H,39,46)(H,40,44)(H,41,45)/t32-,33-,34-,35?/m0/s1
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| InChIKey |
NXLITCKBWIAXEQ-QPMRDEQLSA-N
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| Target and Pathway | |||||
| Target(s) | Renin, renal | Target Info | [1587926] | ||
| Cathepsin D | Target Info | [1587926] | |||
| BioCyc Pathway | Thyroid hormone biosynthesis | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | LKB1 signaling events | ||||
| Ceramide signaling pathway | |||||
| Direct p53 effectors | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| References | |||||
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