Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4XIS
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| Drug Name |
6-(cyclohexylamino)-9-(2-(4-methylpiperazin-1-yl)ethyl)-9H-purine-2-carbonitrile
|
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| Synonyms |
CHEMBL363847
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C19H28N8
|
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| Canonical SMILES |
CN1CCN(CCn2cnc3c(NC4CCCCC4)nc(nc23)C#N)CC1
|
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| InChI |
InChI=1S/C19H28N8/c1-25-7-9-26(10-8-25)11-12-27-14-21-17-18(22-15-5-3-2-4-6-15)23-16(13-20)24-19(17)27/h14-15H,2-12H2,1H3,(H,22,23,24)
|
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| InChIKey |
OGODDSLNRULSMM-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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