Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5CFM
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| Drug Name |
2-[3-(3-{(2-Cyclopropyl-3-[1,2,4]oxadiazol-3-yl-phenyl)-[2-(4-trifluoromethyl-phenyl)-acetyl]-amino}-propyl)-phenoxy]-2-methyl-propionic acid
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| Synonyms |
CHEMBL443218
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C33H32F3N3O5
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| Canonical SMILES |
CC(C)(Oc1cccc(CCCN(C(=O)Cc2ccc(cc2)C(F)(F)F)c3cccc(c3C4CC4)c5nocn5)c1)C(=O)O
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| InChI |
InChI=1S/C33H32F3N3O5/c1-32(2,31(41)42)44-25-8-3-6-21(18-25)7-5-17-39(28(40)19-22-11-15-24(16-12-22)33(34,35)36)27-10-4-9-26(29(27)23-13-14-23)30-37-20-43-38-30/h3-4,6,8-12,15-16,18,20,23H,5,7,13-14,17,19H2,1-2H3,(H,41,42)
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| InChIKey |
YRDLDJLGHRTHHG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Peroxisome proliferator activated receptor gamma | Target Info | [1587926] | ||
| Peroxisomeproliferator activated receptor delta | Target Info | [1587926] | |||
| PANTHER Pathway | CCKR signaling map STP00057:Wnt signaling pathway | ||||
| Pathway Interaction Database | Noncanonical Wnt signaling pathway | ||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Signaling events mediated by HDAC Class I | |||||
| RXR and RAR heterodimerization with other nuclear receptor | |||||
| Regulation of retinoblastoma proteinps1pathway:Presenilin action in Notch and Wnt signaling | |||||
| WikiPathways | Wnt Signaling Pathway Netpath | ||||
| Nuclear Receptors in Lipid Metabolism and Toxicity | |||||
| Differentiation of white and brown adipocyte | |||||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
| Transcriptional Regulation of White Adipocyte Differentiation | |||||
| Adipogenesis | |||||
| SREBP signalling | |||||
| Nuclear ReceptorsWP399:Wnt Signaling Pathway and Pluripotency | |||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Vitamin D Receptor Pathway | |||||
| Ectoderm Differentiation | |||||
| Nuclear Receptors | |||||
| References | |||||
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