Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5DJA
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| Drug Name |
9-isopropyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one
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| Synonyms |
CHEMBL1083350
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H30N4O2
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| Canonical SMILES |
CC(C)n1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6c5cnn6C)c13)C7CCCCO7
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| InChI |
InChI=1S/C28H30N4O2/c1-15(2)32-22-9-7-16(23-6-4-5-11-34-23)12-18(22)25-20-13-29-28(33)26(20)24-17(27(25)32)8-10-21-19(24)14-30-31(21)3/h7,9,12,14-15,23H,4-6,8,10-11,13H2,1-3H3,(H,29,33)
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| InChIKey |
SVRMYHWEROXUTF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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