Drug Information

Drug General Information
Drug ID
DX5FWS
Drug Name
4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-N-cyano-N'-(1-oxy-pyridin-3-ylmethyl)-piperidine-1-carboxamidine
Synonyms
CHEMBL348647
Indication Discovery agent Investigative [1587926]
Formula
C27H25Br2ClN6O
Canonical SMILES
[O-][n+]1cccc(C\\N=C(\\NC#N)/N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)c1
InChI
InChI=1S/C27H25Br2ClN6O/c28-21-10-20-4-3-19-11-22(30)12-23(29)24(19)25(26(20)32-14-21)18-5-8-35(9-6-18)27(34-16-31)33-13-17-2-1-7-36(37)15-17/h1-2,7,10-12,14-15,18,25H,3-6,8-9,13H2,(H,33,34)/t25-/m1/s1
InChIKey
SCQNETOOVNYIJP-RUZDIDTESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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