Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5GZZ
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| Drug Name |
2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(2-imidazol-1-yl-ethoxy)-phenyl]-ethyl}-amide
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| Synonyms |
CHEMBL218007
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H29N7O2
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| Canonical SMILES |
CC(C)(C)CNc1nc(ncc1C(=O)NCCc2ccc(OCCn3ccnc3)cc2)C#N
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| InChI |
InChI=1S/C24H29N7O2/c1-24(2,3)16-29-22-20(15-28-21(14-25)30-22)23(32)27-9-8-18-4-6-19(7-5-18)33-13-12-31-11-10-26-17-31/h4-7,10-11,15,17H,8-9,12-13,16H2,1-3H3,(H,27,32)(H,28,29,30)
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| InChIKey |
HWNYTOPEHDSGOF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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