Drug Information
| Drug General Information | |||||
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| Drug ID |
DX5JLN
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| Drug Name |
N-((S)-4,4-dimethyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopentan-2-yl)furan-2-carboxamide
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| Synonyms |
CHEMBL1807650
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H32N4O6S
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| Canonical SMILES |
C[C@@H]1CC[C@H](NC(=O)[C@H](CC(C)(C)C)NC(=O)c2occc2)C(=O)CN1S(=O)(=O)c3ccccn3
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| InChI |
InChI=1S/C24H32N4O6S/c1-16-10-11-17(19(29)15-28(16)35(32,33)21-9-5-6-12-25-21)26-22(30)18(14-24(2,3)4)27-23(31)20-8-7-13-34-20/h5-9,12-13,16-18H,10-11,14-15H2,1-4H3,(H,26,30)(H,27,31)/t16-,17+,18+/m1/s1
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| InChIKey |
LBCGIKORTZAZTM-SQNIBIBYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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