Drug Information

Drug General Information
Drug ID
DX5LIT
Drug Name
Lithium; (S)-2-({2'-methyl-5-[5-(4-methylsulfanyl-phenyl)-furan-2-ylmethoxymethyl]-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate
Synonyms
CHEMBL11003
Indication Discovery agent Investigative [1587926]
Formula
C32H32NO5S2.Li
Canonical SMILES
[Li+].CSCC[C@H](NC(=O)c1ccc(COCc2oc(cc2)c3ccc(SC)cc3)cc1c4ccccc4C)C(=O)[O-]
InChI
InChI=1S/C32H33NO5S2.Li/c1-21-6-4-5-7-26(21)28-18-22(8-14-27(28)31(34)33-29(32(35)36)16-17-39-2)19-37-20-24-11-15-30(38-24)23-9-12-25(40-3)13-10-23;/h4-15,18,29H,16-17,19-20H2,1-3H3,(H,33,34)(H,35,36);/q;+1/p-1/t29-;/m0./s1
InChIKey
ZDPUFIWRLCGOGH-JMAPEOGHSA-M
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.