Drug Information

Drug General Information
Drug ID
DX5OGA
Drug Name
1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-phenyl-propan-1-one
Synonyms
CHEMBL368752
Indication Discovery agent Investigative [1587926]
Formula
C28H30ClN3O
Canonical SMILES
CC(C)(C(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cccnc24)c5ccccc5
InChI
InChI=1S/C28H30ClN3O/c1-28(2,22-8-4-3-5-9-22)27(33)32-17-15-31(16-18-32)26-24-13-12-23(29)19-21(24)11-10-20-7-6-14-30-25(20)26/h3-9,12-14,19,26H,10-11,15-18H2,1-2H3
InChIKey
ZNGBFAOFMLQVNQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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