Drug Information

Drug General Information
Drug ID
DX5TRD
Drug Name
1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2,2-diphenyl-ethanone
Synonyms
CHEMBL171938
Indication Discovery agent Investigative [1587926]
Formula
C32H30ClN3O
Canonical SMILES
Clc1ccc2C(N3CCN(CC3)C(=O)C(c4ccccc4)c5ccccc5)c6ncccc6CCc2c1
InChI
InChI=1S/C32H30ClN3O/c33-27-15-16-28-26(22-27)14-13-25-12-7-17-34-30(25)31(28)35-18-20-36(21-19-35)32(37)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-12,15-17,22,29,31H,13-14,18-21H2
InChIKey
FBAAQDIYOZAXRT-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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